Maria Isabel de Bragança, Infanta of Portugal, Queen of Spain - by Vicente López y Portaña, circa 1816-18

Maria Isabel Francisca de Bragança (19 May 1797 – 26 December 1818), Infanta of Portugal, Queen of Spain as the second wife of Ferdinand VII.  She was the major force behind the founding of what came to be the Museo del Prado.  She died, horrifically, in childbirth at the age of twenty-one, a year before the museum opened to the public.

"Maria Isabel of Portugal in front of the Prado" by Bernardo López y Piquer (1799-1874), 1829.  This portrait was painted eleven years after the queen's 
death, and commemorates her important involvement in the founding the Museo del Prado.  The artist obviously used the portrait by López y Portaña -  
who was López y Piquer's father - as the model for the deceased queen.